E2 Dispensing, for the first time moves the packaging and labeling of investigational drug from a product-centric model to a patient-centric model. In this new model, drug supplies are dispensed to patients by a pharmacist from a central-fill pharmacy, according to the requirements and regulations of the practice of pharmacy rather than packaged by trained individuals according to the requirements of Good Manufacturing Practices.

Why Pharmacists?

Simple, Effective, Cost-Efficient

E2 Dispensing eliminates unnecessary and redundant steps, delivering a simple, more efficient clinical supply chain. Clinical supplies are labeled and dispensed with a familiar, patient-friendly pharmacy prescription label, improving the quality of compliance and adherence.

E2 Dispensing not only reduces packaging, labeling, distribution, and storage costs, but also leads to a lower burden on Project Managers for planning, forecasting, and implementation as a result of the simplified supply process.

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Current Process

E2 Dispensing Process


Clinical research is a complicated process, but E2 Dispensing makes it simple.
Check out our E2 Dispensing FAQ to learn how simple switching to E2 Trials can be.


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Time, Cost, Quality

E2 Dispensing eliminates costs associated with unnecessary planning, packaging and labeling of clinical supplies.
Our most current pricing shows up to a 50% cost savings. Request a quote and see for yourself.

Why Pharmacists

Utilizing Trusted Medication Experts

Today’s pharmacies are untapped resources. Pharmacists build lifetime relationships with their patients on a foundation of trust and one-on-one patient care. RxE2 understands the importance of these relationships and the vital role of the pharmacist in dispensing, compliance, adherence, and retention. The practice of pharmacy is the cornerstone of RxE2’s E2 Dispensing services.

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Time, Cost & Quality

E2 Dispensing redefines how we think about time, cost and quality of the clinical supply chain model


A large part of what clinical supply project managers do for traditional clinical supplies packaging and labeling process focuses on how to make the GMP process work for individual protocols while considering how clinical sites will remain blinded when dispensing GMP material to patients.   Whole departments have been created to ensure the success of this planning process, while large GMP manufacturing facilities have been created and are dedicated to clinical supplies packaging and labeling  to produce what the project managers have created to meet clinical protocol requirements.  All of this takes time.  Time to plan, time to manufacture, and time to get clinical supplies to patients.

E2 Dispensing eliminates almost all of the time needed for project management, time for specialized packaging and labeling operations, and time to get supplies to the patient.  This is done just by incorporating the practice of pharmacy into clinical research.

E2 Dispensing requires that open label, bulk drug be sent to a central-fill pharmacy where pharmacists will dispense medication according to a medical order outlined in the clinical protocol or pharmacist manual.  Instead of taking 3-6 months to get clinical supplies to patients, E2 Dispensing take 3-6 days.


There are so many ways to show how E2 Dispensing will save costs, the least of which is the elimination of the costs associated with unnecessary planning, packaging and labeling of clinical supplies.  For most, costs come down to a direct comparison of what it costs today to use the current traditional packaging and labeling method compared to what E2 Dispensing will cost.  Current pricing shows up to a 50% cost savings.  Ask for a quote and see this for yourself.


E2 Dispensing greatly improves the quality of clinical supplies being dispensed to patients.  First and foremost, the pharmacist, the medication expert, will be counseling the patient according to state law requirements and ensure that the right drug was delivered to the right patient and that the patient knows how to use and store the medication.  Secondly, the clinical supplies will be labeled with a patient specific pharmacy label rather than a GMP-type label, providing the patient with the information they need to properly take the medication.

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Dive into E2 Dispensing with us

Watch all episodes of our E2 Dispensing webinar to learn more about our approach